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Foram relatados casos de reações graves, às vezes fatais, com a administração concomitante de ISRS e inibidores da MAO, incluindo
hipertermia, rigidez, mioclonia, distúrbios do sistema nervoso autônomo com possíveis transformações rápidas nas funções vitais, e mudanças no estado mental,
incluindo excitação intensa que pode progredir pra delírio e coma.
A administração concomitante de dapoxetina e tamoxifeno
não causou modificações no perfil ortostático e
nos efeitos ortostáticos em comparação com o exercício de tamoxifeno isolado ou com dapoxetina
em doses de trinta ou sessenta mg. Como por exemplo, as taxas de impotência
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conduzir a um acrescento significativo da exibição à dapoxetina
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Esse acrescentamento é aproximado ao visto em metabolizadores lentos do
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